Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as reduction in hypertrophic response at 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as reduction in BNP-promoter driven activity at 10 to 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method
Modulation of GATA4/NKX2-5 protein-protein interaction in neonatal Wistar rat cardiomyocytes harboring -534/+4 bp rat BNP proximal promoter assessed as increase in BNP-promoter driven activity at 10 to 30 preincubated for 1 hr followed by hypertrophic agonist endothelin-1 and measured after 24 hrs by luminescence method
Assay data:2 Active, 2 Tested
Enhancement of mouse GATA4 expressed in Chlorocebus aethiops COS1 cells harboring NP-112 reporter gene assessed as BNP promoter-driven transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Assay data:10 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mouse GATA4 expressed in Chlorocebus aethiops COS1 cells harboring NP-112 reporter gene assessed as BNP promoter-driven transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Enhancement of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Inhibition of mouse GATA4/mouse NKX2-5 protein-protein interaction expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as transcriptional synergy at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Enhancement of mouse GATA4/mouse NKX2-5 protein-protein interaction expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as transcriptional synergy at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Modulation of mouse GATA4 expressed in Chlorocebus aethiops COS1 cells harboring NP-112 reporter gene assessed as BNP promoter-driven transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Assay data:97 Tested
Modulation of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Modulation of mouse GATA4/mouse NKX2-5 protein-protein interaction expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as transcriptional synergy at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Assay data:99 Tested
Inhibition of mouse NKX2-5 expressed in Chlorocebus aethiops COS1 cells harboring 3xHA reporter gene assessed as protein-induced transcriptional activity at 10 uM after 24 hrs by luciferase reporter gene assay relative to control
Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of BNP at 100 uM after 24 hrs by real-time PCR analysis relative to control
Assay data:1 Tested
Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of ANP at 100 uM after 24 hrs by real-time PCR analysis relative to control
Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in endothelin-1 induced mRNA level of BNP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis relative to control
Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of BNP at 20 uM after 24 hrs by real-time PCR analysis relative to control
Activation of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as increase in basal mRNA level of ANP at 20 uM after 24 hrs by real-time PCR analysis relative to control
Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of BNP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis
Inhibition of GATA4/NKX2-5 interaction in neonatal rat ventricular cardiomyocytes assessed as decrease in endothelin-1 induced mRNA level of ANP at 20 uM preincubated for 1 hr followed by endothelin-1 addition measured after 23 hrs by real-time PCR analysis
Assay data:4 Active, 4 Tested
Inhibition of mouse GATA4-driven transactivation of luciferase reporter construct containing BNP minimal promoter with tandem GATA-site on -90 bp expressed in African green monkey COS-1 cells after 30 hrs by luminometer
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on