Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity to alphaA (66 to 80 residues) crystallin peptide in aqueous solution assessed as gibbs free energy change at 1 mM by isothermal titration calorimetry
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to alphaA (66 to 80 residues) crystallin peptide in aqueous solution assessed as change in entropy at 1 mM by isothermal titration calorimetry
Binding affinity to alphaA (66 to 80 residues) crystallin peptide in aqueous solution assessed as change in enthalpy at 1 mM by isothermal titration calorimetry
Binding affinity to alphaA (66 to 80 residues) crystallin peptide in aqueous solution assessed as association constant at 1 mM by isothermal titration calorimetry
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation assessed as decrease in peptide-receptor complex and measured after 72 hrs by ESI-MS analysis
Assay data:1 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation assessed as decrease in peptide-receptor complex and measured upto 2 hrs by ESI-MS analysis
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation assessed as amorphous small protein aggregates at 1:1 peptide to ligand ratio incubated for 7 days by transmission electron microscopy
Assay data:3 Active, 3 Tested
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation assessed decrease in large fibrillar aggregation at 1:1 peptide to ligand ratio incubated for 7 days by transmission electron microscopy
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation assessed as decrease in average diameter size distribution at 1:1 peptide to ligand ratio incubated for 7 days by fluorescence aggregation assay (Rvb=12000+/-1500 nm)
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation incubated for 7 days by fluorescence aggregation assay
Inhibition of alphaA (66 to 80 residues) crystallin peptide aggregation at peptide to ligand ratio of 0.2 to 5:1 incubated for 7 days by fluorescence aggregation assay
Inhibition of alpha-crystallin A Y118D mutant (unknown origin)-induced cytotoxicity in human HLE-B3 cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay
Assay data:5 Active, 5 Tested
Inhibition of alpha-crystallin A Y118D mutant (unknown origin)-induced cytotoxicity in human HeLa cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay
Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) at 200 uM incubated for 24 hrs by transmission-electron-microscopy
Assay data:1 Active, 2 Tested
Induction of redissolving of aggregated alpha-crystallin A R116H mutant (unknown origin) at 200 uM incubated for 24 hrs by transmission-electron-microscopy
Induction of redissolving of aggregated alpha-crystallin A R116C mutant (unknown origin) at 200 uM incubated for 24 hrs by transmission-electron-microscopy
Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) at 200 uM incubated for 24 hrs by ThT-fluorescence based assay
Induction of redissolving of aggregated alpha-crystallin A R116H mutant (unknown origin) at 200 uM incubated for 24 hrs by ThT-fluorescence based assay
Induction of redissolving of aggregated alpha-crystallin A R116C mutant (unknown origin) at 200 uM incubated for 24 hrs by ThT-fluorescence based assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on