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Mouse TRH2 receptor (Thyrotropin-releasing hormone receptors)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Rat TRH2 receptor (Thyrotropin-releasing hormone receptors)
Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cell membranes at 30 uM after 4 hrs by scintillation counting method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISA
Assay data:13 Active, 11 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assay
Assay data:14 Active, 5 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 16 Tested
Displacement of [3H]-Me-His-TRH from mouse TRH-R2 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrs
Assay data:6 Active, 3 Activity ≤ 1 µM, 16 Tested
Agonist activity at mouse TRH-R2 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR method
Assay data:18 Active, 1 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 18 Tested
Displacement of [3H]-1-MeHis-TRH from mouse TRH-R2 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 µM, 18 Tested
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