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Glutamate, NMDA, Glycine Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Glutamate, NMDA, Agonism Eurofins Panlabs panel
NMDA/R Eurofins SafetyScreen44 (BI)
Antagonist activity at NMDA receptor (unknown origin) assessed as inhibition constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Positive allosteric modulator activity at NMDA receptor in rat Hippocampal neurone
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [3H]ifenprodyl from NMDA receptor (unknown origin)
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]MDL from NMDA receptor (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a assessed as maximum potentiation at 30 uM in the presence of L-glutamate and glycine by Ca2+ influx assay
Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glutamate and glycine by Ca2+ influx assay
Blocking of NMDA receptor in mouse fibroblast assessed as inhibition of NMDA-induced excitotoxicity by LDH release assay
Inhibition of NMDA receptor (unknown origin) at 10 uM
Binding affinity to TCP-stimulated NMDA (unknown origin)
Binding affinity to NMDA receptor (unknown origin)
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of NMDA receptor in NMDA-stimulated rat cerebellar granule neurons assessed as measuring intracellular calcium concentration in presence of glycine by Fura2-AM dye based fluorescence assay
Assay data:1 Active, 13 Tested
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