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Inhibition of Dopamine beta-hydroxylase (unknown origin) incubated for 10 mins
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of bovine adrenal medulla DBH at 0.005 uM relative to control
Inhibition of bovine adrenal medulla DBH at 0.05 uM relative to control
Inhibition of bovine adrenal medulla DBH at 1 uM relative to control
Inhibition of bovine adrenal medulla DBH at 0.5 uM relative to control
Assay data:2 Tested
Inhibition of bovine adrenal medulla DBH at 5 uM relative to control
Inhibition of bovine adrenal medulla DBH incubated for 25 mins
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Human Dopamine beta-hydroxylase (dopamine beta-monooxygenase) (Catecholamine turnover)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of dopamine beta-oxygenase (unknown origin)
Assay data:3 Active, 3 Tested
Inhibition of bovine adrenal medullae dopamine-beta-hydroxylase
Assay data:20 Tested
Inhibition of bovine adrenal dopamine beta-hydroxylase at 0.1 mM
Inhibition of bovine adrenal dopamine beta-hydroxylase at 0.2 mM
Inhibition of bovine adrenal dopamine beta-hydroxylase assessed as norepinephrine formation per mg of protein at 0.1 mM after 45 mins
Inhibition of bovine adrenal dopamine beta-hydroxylase assessed as norepinephrine formation per mg of protein at 0.2 mM after 45 mins
Effect on DBH activity in presence of dopamine by measuring Noradrenaline level
Assay data:30 Tested
Kinetic parameter kcat was measured for dopamine beta-monooxygenase
Assay data:4 Tested
Kcat/Km value of the compound
Kinetic parameter Km was measured for dopamine beta-monooxygenase
Inhibition of dopamine beta-hydroxylase (DbetaH) enzyme
Assay data:9 Active, 2 Activity ≤ 1 µM, 47 Tested
Inhibitory activity towards dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneally activity expressed as log IC50; nd=No data
Assay data:3 Tested
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