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% Enzyme Activity of MMP1 in the Reaction Biology protease panel at 1.0 M
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of recombinant human MMP1 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substrate preincubated with compound for 15 mins followed by substrate addition and measured after 1 hrs by fluorescence based analysis
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant MMP1 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 15 mins followed by substrate addition and measured after 120 mins by fluorescence based assay
Assay data:1 Tested
Assay for Inhibition of MMP from US Patent US20240050571: "CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE INHIBITORS AND AGENTS FOR BORON NEUTRON CAPTURE THERAPY"
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of human MMP-1 at 100 uM relative to control
Inhibition of human MMP-1
Assay data:5 Tested
Inhibition of MMP1 (unknown origin) at 50 uM relative to control
Inhibition of MMP1 (unknown origin)
Assay data:3 Tested
Inhibition of human MMP1 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate preincubated for 0.5 hrs followed by substrate addition and measured after 6 hrs by fluorimeter analysis
Inhibition of MMP-1 (unknown origin) by fluorimetric assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of recombinant human MMP1 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of recombinant human MMP1 expressed in Escherichia coli BL21 (DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20 to 30 mins by fluorescence assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of human MMP1 using Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(Nma)-NH2 substrate by fluorimetric analysis
Inhibition of MMP-1 (unknown origin)
Assay data:11 Active, 8 Activity ≤ 1 µM, 11 Tested
Inhibition of human recombinant MMP-1 assessed as inhibition constant
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of MMP-1 (unknown origin) assessed as inhibition constant
Assay data:4 Active, 2 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 5 Tested
Inhibition of MMP-1 in human Rheumatoid Synovial fibroblasts using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated with enzyme for 3 hrs followed by substrate addition and measured every 10 secs for 15 mins by fluorescence based analysis
Assay data:4 Tested
Assay data:2 Active, 3 Activity ≤ 1 µM, 3 Tested
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