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Cytotoxicity against human CHP100 cells assessed as viable cell after 24 hrs by MTT assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Effect on human F-actin pellet formation after 1 hr by SDS-PAGE
Assay data:1 Tested
SummaryPubMed Citation
Effect on human F-actin bundling assessed as light scattering after 1 hr by SDS-PAGE
Displacement of biotinyl-withaferin from annexin-2 in human CHP100 at 0.4 to 4 uM by chemiluminescence assay
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of biotinyl-withaferin from annexin-2 in human MCF10A at 0.4 to 4 uM by chemiluminescence assay
Cytotoxicity against human HepG2 cells harboring annexin 2 assessed as rapid shape change and rounding up at 4 uM after 2 hrs
Cytotoxicity against human PC3M cells assessed as viable cell after 24 hrs by MTT assay
Cytotoxicity against human WI38 cells assessed as cell viability pretreated after 16 hrs by MTT assay in presence of 1 uM cytochalasin B
Cytotoxicity against human WI38 cells assessed as cell viability pretreated after 16 hrs by MTT assay in presence of 0.5 uM cytochalasin B
Cytotoxicity against human HepG2 cells harboring annexin 2 after 48 hrs by MTT assay
Induction of annexin 2-mediated cytoskeleton aggregate accumulation in human HepG2 cells at 4 uM after 2 hrs by confocal laser scanning microscopy
Induction of annexin 2-mediated F-actin disruption in human HepG2 cells at 4 uM after 2 hrs by confocal laser scanning microscopy
Induction of annexin 2-mediated F-actin disruption in human WI38 cells at 4 uM after 2 hrs by confocal laser scanning microscopy
Effect on human annexin 2-mediated F-actin bundling assessed as increase in light scattering after 1 hr by SDS-PAGE
Inhibition of annexin 2-mediated liposome aggregation after 15 mins by spectrophotometry
Assay data:1 Active, 2 Tested
Binding affinity to annexin 2 assessed as inhibition of protein-lipid interaction after 15 mins by coomassine blue staining
Displacement of biotinyl-withaferin from bovine lung annexin 6 at 10 uM by chemiluminescence assay
SummaryPubMed CitationRelated BioAssays by Target
Displacement of biotinyl-withaferin from bovine lung annexin 4 at 10 uM by chemiluminescence assay
Displacement of biotinyl-withaferin from bovine lung annexin 5 at 10 uM by chemiluminescence assay
Displacement of biotinyl-withaferin from bovine lung annexin 2 at 10 uM by chemiluminescence assay
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