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Wombat Data for BeliefDocking
Assay data:3482 Active, 6170 Tested
SummaryCompounds, ActivePubMed Citation
Selectivity determined as the ratio of IC50 trypsin/IC50 Xa
Assay data:19 Tested
SummaryPubMed Citation
Inhibitory concentration against trypsin
Assay data:17 Active, 16 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Percent inhibition of thrombosis at the dose of 50 ug/kg in rabbit deep vein thrombosis model
Assay data:1 Tested
Percent inhibition of thrombosis at the dose of 25 ug/kg in rabbit deep vein thrombosis model
Percent inhibition of thrombosis at the dose of 100 ug/kg in rabbit deep vein thrombosis model
Plasma concentration at the dose of 100 ug/kg in rabbit
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibitory concentration against factor IIa
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of factor II
Assay data:2 Active, 2 Activity ≤ 1 µM, 15 Tested
Binding affinity towards factor Xa
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibitory concentration to factor Xa
Assay data:28 Active, 1 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 30 Tested
Bioavailability in rat at an oral dose of 2 mg/kg
Half-life period in rats following intravenous administration at 2 mg/kg
Half-life period in rabbits following intravenous administration at 2 mg/kg
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