Related BioAssays, by Same Publication (List) for PubChem BioAssay (Se - PubChem BioAssay - NCBI

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Items: 17

Select item 19424891.

Cytotoxicity against BRAF mutant human A-375 cells

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942489

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19424882.

Inhibition of recombinant full length His-tagged human Aurora A expressed in baculovirus expression system by FRET assay

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942488

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19424873.

Inhibition of recombinant full length His-tagged human PDK1 expressed in baculovirus expression system by FRET assay

Source:: ChEMBL

Protein Target:: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942487

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19424864.

Inhibition of human MEK2

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942486

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19424855.

Inhibition of human MEK1

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942485

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19424846.

Inhibition of human Aurora C

Source:: ChEMBL

Protein Target:: Aurora kinase C

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942484

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19424837.

Inhibition of Xenopus laevis Aurora kinase B

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942483

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19424828.

Inhibition of human Aurora A

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942482

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19424819.

Inhibition of Src (unknown origin)

Source:: ChEMBL

Protein Target:: Proto-oncogene tyrosine-protein kinase Src

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942481

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194248010.

Antitumor activity against human Fuji cells xenografted in mouse assessed as reduction in tumor weight

Source:: ChEMBL

Assay data:1 Tested

AID:: 1942480

Summary PubMed Citation

Select item 194247911.

Antitumor activity against human Fuji cells xenografted in mouse assessed as reduction in tumor volume

Source:: ChEMBL

Assay data:1 Tested

AID:: 1942479

Summary PubMed Citation

Select item 194247812.

Inhibition of JAK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1942478

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194247713.

Antitumor activity against human A-375 cells xenografted in mouse assessed as tumor growth inhibition

Source:: ChEMBL

Assay data:1 Tested

AID:: 1942477

Summary PubMed Citation

Select item 194247614.

Inhibition of Aurora B (unknown origin)

Source:: ChEMBL

Protein Target:: Aurora kinase B

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1942476

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194247515.

Inhibition of Aurora A (unknown origin)

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1942475

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194247416.

Inhibition of CDK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent kinase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942474

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194247317.

Inhibition of CDK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Cyclin-dependent kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1942473

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioActivity

Active Compounds (14)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (14)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (14)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (17)
BioAssays extracted from the literature

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