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Probe Development Summary for Inhibitors of RGS12 GoLoco Motif Activity
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions.
Assay data:1629 Active, 1629 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
Assay data:218702 Tested
Single point concentration, multiplexed high-throughput screen for confirmation of small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
Assay data:73 Active, 1658 Tested
Single point concentration, multiplexed high-throughput screen for confirmation of small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
Assay data:75 Active, 1658 Tested
Single point concentration, multiplexed high-throughput screen for confirmation of small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
Assay data:129 Active, 1658 Tested
Single point concentration, multiplexed high-throughput screen for confirmation of small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
Assay data:48 Active, 1658 Tested
Counter screen for biotinylated proteins binding to avidin beads
Assay data:1658 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Profiling compound fluorescence on Avidin Beads with 488 nm excitation and 530 nm emission
Assay data:825 Active, 217624 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
Assay data:826 Active, 218702 Tested
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
Assay data:50 Active, 185 Tested
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
Assay data:770 Active, 218702 Tested
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
Assay data:750 Active, 218702 Tested
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao.
Assay data:711 Active, 218702 Tested
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore)
Assay data:1029 Active, 234161 Tested
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Green Fluorophore)
Assay data:12 Active, 3 Activity ≤ 1 µM, 1279 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Compound Screen Assay, Human RGS18
Assay data:2 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Single point concentration, multiplexed high-throughput screen for confirmation of small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.
Assay data:89 Active, 1658 Tested
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao with additional round of SAR compounds.
Assay data:5 Tested
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
Assay data:30 Active, 7 Activity ≤ 1 µM, 185 Tested
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