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Summary of Broad Institute MLPCN Beta Cell Apoptosis Inhibition Project
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Detect Cellular ATP-levels in INS-1E Cells Measured in Cell-Based System Using Plate Reader - 2061-01_Inhibitor_SinglePoint_HTS_Activity
Assay data:26 Active, 19828 Tested
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Beta Cell Apoptosis.
Assay data:2443 Active, 303588 Tested
Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis
Assay data:2165 Active, 246 Activity ≤ 1 µM, 2288 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Luminescence Cell-Based Counter Screen to Identify Inhibitors of Cytokine Induced Apoptosis
Assay data:167 Active, 4 Activity ≤ 1 µM, 2288 Tested
ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick
Assay data:2065 Active, 111 Activity ≤ 1 µM, 2288 Tested
Detect Cellular ATP-levels in INS-1E Cells Measured in Cell-Based System Using Plate Reader - 2061-01_Inhibitor_Dose_DryPowder_Activity
Assay data:36 Active, 1 Activity ≤ 1 µM, 88 Tested
Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-02_Inhibitor_Dose_DryPowder_Activity
Assay data:8 Active, 1 Activity ≤ 1 µM, 35 Tested
ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_DryPowder_Activity
Assay data:2 Active, 88 Tested
Nitrite Measured in Cell-Based System Using Plate Reader - 2061-04_Inhibitor_Dose_DryPowder_Activity
Assay data:7 Active, 35 Tested
Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-03_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:15 Active, 88 Tested
Nitrite Measured in Cell-Based System Using Plate Reader - 2061-04_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:30 Active, 80 Tested
Nitrite Measured in Cell-Based System Using Plate Reader - 2061-04_Inhibitor_Dose_DryPowder_Activity_Set3
Assay data:27 Active, 86 Tested
Effects of siRNA knock down of Usp9x (a target of ML-187) on cytokine-induced apoptosis (Caspase activity) Measured in Cell-Based System Using Plate Reader
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-03_Inhibitor_Dose_DryPowder_Activity
Assay data:26 Active, 86 Tested
Apoptosis Measured in Cell-Based System Using Plate Reader - 2061-02_Inhibitor_Dose_DryPowder_Activity_Set2
Assay data:4 Active, 88 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Primary Beta Cell Apoptosis assay Measured in Cell-Based System Using Plate Reader - 2061-07_Inhibitor_Dose_DryPowder_Activity_Set2
Primary beta islet insulin ELISA Measured in Cell-Based System Using Plate Reader - 2061-09_Inhibitor_Dose_DryPowder_Activity
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Glucose-induced Insulin secretion ELISA Measured in Cell-Based System Using Plate Reader - 2061-05_Inhibitor_Dose_DryPowder_Activity
Quantitative proteomics to determine protein binders to ML187
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