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Summary of probe development efforts to identify inhibitors of the p97 ATPase.
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of p97-independent reporter turnover
Assay data:12 Active, 21 Tested
Caspase 3/7 Activation in response to p97 inhibition
Assay data:5 Active, 24 Tested
p97 ATPase dose response - Hit Optimization Round 3
Assay data:45 Active, 24 Activity ≤ 1 µM, 65 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibition of proteasomal turnover of a p97-dependent reporter substrate in human cells - Hit Optimization Round 3
Assay data:40 Active, 2 Activity ≤ 1 µM, 65 Tested
Inhibition of proteasomal turnover of a p97-dependent reporter substrate in human cells - Hit Optimization Round 2
Assay data:27 Active, 84 Tested
p97 ATPase dose response - Hit Optimization Round 2
Assay data:50 Active, 12 Activity ≤ 1 µM, 86 Tested
Inhibition of proteasomal turnover of a p97-dependent reporter substrate in human cells
Assay data:32 Active, 56 Tested
p97 ATPase dose response
Assay data:20 Active, 29 Tested
Late stage results from the probe development effort to identify inhibitors of the p97 ATPase.
Assay data:3 Active, 12 Tested
Luminescence counterscreen assay for p97 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of the C522A mutant p97 ATPase: synthesized compounds.
Assay data:16 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Luminescence dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase: synthesized compounds.
Assay data:1 Active, 16 Tested
Luminescence counterscreen assay for p97 inhibitors: Dose response biochemical high throughput screening assay to identify inhibitors of the C522A mutant p97 ATPase.
Assay data:1 Active, 54 Tested
Dose response biochemical high throughput screening assay for inhibitors of the p97 ATPase
Assay data:5 Active, 54 Tested
Confirmation biochemical high-throughput screening assay for inhibitors of the p97 ATPase
Assay data:333 Active, 759 Tested
Primary biochemical high-throughput screening assay to measure P97 ATPase inhibition
Assay data:925 Active, 218117 Tested
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