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Late stage assay provider QFRET-based biochemical high throughput dose response assay to counterscreen inhibitors of ADAM10 and ADAM17 against metalloproteases MMP1, MMP2, MMP8, MMP9, MMP10, MMP13, MMP14, Meprin A, and Meprin B
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Late stage QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM10.
Assay data:3 Active, 24 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
QFRET-based biochemical high throughput dose response assay to identify exosite inhibitors of ADAM10.
Assay data:49 Active, 1 Activity ≤ 1 µM, 235 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counterscreen for exosite inhibitors of ADAM10: QFRET-based biochemical high throughput dose response assay to identify inhibitors of ADAM17
Assay data:3 Active, 1 Activity ≤ 1 µM, 235 Tested
QFRET-based biochemical high throughput confirmation assay to identify exosite inhibitors of ADAM10.
Assay data:31 Active, 2125 Tested
Summary of a probe development effort to identify exosite inhibitors of ADAM10
QFRET-based biochemical primary high throughput screening assay to identify exosite inhibitors of ADAM10.
Assay data:2294 Active, 370276 Tested
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