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Inhibition of CDK1/cyclin E (unknown origin) at 10 uM by biochemical hotspot kinase assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of AKT1 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Inhibition of AKT1 (unknown origin) in presence of ATP by ELISA
Assay data:4 Tested
Inhibition of calmodulin (unknown origin)
Assay data:2 Tested
Inhibition of CDK2/cyclin E1 (unknown origin) expressed in Sf9 cells
Assay data:2 Active, 9 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of CDK2/cyclin E (unknown origin)
Assay data:5 Active, 10 Tested
Inhibition of AKT1 (unknown origin) at 1 uM relative to control
Assay data:3 Tested
Binding affinity to HSP90 (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of CDK2/Cyclin E (unknown origin)
Assay data:10 Active, 6 Activity ≤ 1 µM, 10 Tested
Inhibition of CDK2/Cyclin E (unknown origin) at 500 nM
Assay data:32 Tested
Inhibition of CDK2/Cyclin E1 (unknown origin) assessed as inhibition of substrate peptide phosphorylation using eIF4E-binding protein 1 as peptide substrate incubated for 4 hrs in presence of ATP by Lance Ultra HTRF assay
Assay data:17 Active, 13 Activity ≤ 1 µM, 24 Tested
Inhibition of AKT1 (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of AKT expression in human MDA-MB-231 cells at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis
Inhibition of AKT phosphorylation in human MDA-MB-231 cells at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis
Inhibition of AKT phosphorylation in human Jurkat cells incubated for 1 to 12 hrs by Western blot analysis relative to control
Inhibition of AKT phosphorylation in human THP-1 cells incubated for 1 to 12 hrs by Western blot analysis relative to control
Inhibition of AKT phosphorylation in human Jurkat cells at 1 uM incubated for 1 to 12 hrs by Western blot analysis relative to control
Assay data:1 Active, 1 Tested
Inhibition of AKT phosphorylation in human THP-1 cells at 1 uM incubated for 1 to 12 hrs by Western blot analysis relative to control
Binding affinity to amyloid beta (1 to 40) (unknown origin) aggregates assessed as dissociation constant
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Disaggregation of Fe3+ induced Amyloid beta (1 to 42) (unknown origin) aggregation at 100 uM incubated for 24 hrs by ThioflavinT-dye based fluorescence analysis
Assay data:5 Active, 5 Tested
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