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qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: HTRF Assay
Assay data:56 Active, 2 Activity ≤ 1 µM, 206 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Texas Red FP
Assay data:90 Active, 6 Activity ≤ 1 µM, 201 Tested
qHTS Fluorescence Polarization (FP) Assay for Inhibitors of MLL CXXC domain - DNA interaction: Fluorescein FP
Assay data:140 Active, 26 Activity ≤ 1 µM, 201 Tested
Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Confirmation in an MLL leukemia cell growth assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Inhibitor SAR for Compounds Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide
Assay data:22 Active, 4 Activity ≤ 1 µM, 104 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Binding Confirmation with NMR Saturation Transfer Difference
Assay data:9 Active, 28 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction: Summary
SummaryRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Summary
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide
Assay data:24 Active, 342 Tested
Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide
Assay data:51 Active, 342 Tested
Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Confirmation in an HTRF (commercial TR-FRET) Assay using His-tagged menin and biotin-labeled MLL peptide
Assay data:23 Active, 342 Tested
qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction
Assay data:110 Active, 1 Activity ≤ 1 nM, 559 Activity ≤ 1 µM, 294978 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide
Assay data:615 Active, 1 Activity ≤ 1 nM, 686 Activity ≤ 1 µM, 266676 Tested
qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide
Assay data:137 Activity ≤ 1 µM, 292510 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Confirmation of Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: NMR spectroscopy to verify direct binding of compounds to menin
Assay data:13 Active, 63 Tested
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