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Inhibition concentration required to inhibit rat liver histone deacetylase (HDAC) in the presence of compound 5e as a substrate
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of in vitro enzyme activity measured in partially purified rat liver Histone deacetylase preparation
Assay data:22 Active, 18 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibitory activity against histone deacetylase (HDAC)
Assay data:3 Active, 3 Activity ≤ 1 µM, 4 Tested
Inhibitory concentration against rat liver Histone deacetylase
Assay data:25 Active, 22 Activity ≤ 1 µM, 26 Tested
Inhibitory activity against rat liver Histone deacetylase with substrate 3a
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibitory activity against rat liver Histone deacetylase with substrate 3b
Inhibitory activity against rat liver Histone deacetylase with substrate 5b
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3b
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5a
Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3a
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5b
Inhibition of HDAC in rat liver by fluorimetry
Assay data:3 Active, 2 Activity ≤ 1 µM, 12 Tested
Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 12a
Inhibition of HDAC in rat liver homogenate
Assay data:17 Active, 17 Activity ≤ 1 µM, 18 Tested
Inhibition of rat liver HDAC at 10 uM pre-incubated for 15 mins before Boc-Lys(Ac)-AMC substrate addition and measured after 30 mins by fluorometry
Assay data:44 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of rat liver HDAC at 0.1 uM pre-incubated for 15 mins before Boc-Lys(Ac)-AMC substrate addition and measured after 30 mins by fluorometry
Displacement of [125I]human ghrelin from rat GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting method
Inhibition of HDAC in rat C6 cells assessed as increase in histone H3 acetylation at 5 uM after 6 hrs by flow cytometry (Rvb = 4.5%)
Assay data:5 Tested
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