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Inhibition of Src phosphorylation in rat RBL-2H3 cells assessed as inhibition of Fc epsilonRI-mediated signal transduction by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Src in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as suppression of LPS-induced microglia activation by measuring Iba-1 expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 5 hrs by ELISA
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of LPS-induced Src phosphorylation at Tyr-416 residue in Sprague-Dawley rat primary microglia cells at 10 uM preincubated for 1 hr followed by LPS stimulation measured after 3 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
Inhibition of Src in Sprague-Dawley rat primary microglia cells assessed as suppression of LPS-stimulated Akt phosphorylation at Ser-473 residue at 10 uM preincubated for 1 hr followed by LPS challenge measured after 3 hrs by Western blot analysis
Inhibition of Src in Sprague-Dawley rat primary microglia cells assessed as suppression of LPS-stimulated PTEN phosphorylation at Tyr-240 residue at 10 uM preincubated for 1 hr followed by LPS challenge measured after 3 hrs by Western blot analysis
Inhibition of SRC in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as protection against LPS-induced dopaminergic neuro-toxicity by measuring TH expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 7 days by Western blot analysis
Inhibition of Src in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as suppression of LPS-induced TNFalpha expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 5 hrs by ELISA
Inhibition of Src in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as suppression of LPS-induced IL-1beta expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 5 hrs by ELISA
Inhibition of Src in rat fibroblasts
Assay data:11 Active, 8 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr (not tested)
Assay data:3 Tested
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposure
Assay data:14 Active, 20 Activity ≤ 1 µM, 20 Tested
Inhibition of src kinase activity in Src transformed rat fibroblasts
Assay data:5 Active, 1 Activity ≤ 1 µM, 12 Tested
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