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In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 1.25 uM after 6 h
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
KI for pyridoxal 5'-phosphate (PLP)-dependent Gamma-amino-N-butyrate transaminase at pH 7.4
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Kinact for pyridoxal 5'-phosphate (PLP)-dependent Gamma-amino-N-butyrate transaminase at pH 7.4
Assay data:1 Tested
Percent inhibition of Gamma-amino-N-butyrate transaminase from rat was evaluated
Percent inhibition of Gamma-amino-N-butyrate transaminase from rat was evaluated; ND is no data
Percent of enzyme inhibition by Gamma-amino-N-butyrate transaminase assay method
Assay data:3 Tested
Percent of enzyme inhibition by Gamma-amino-N-butyrate transaminase assay method ND means no data
Percent of enzyme inhibition by Gamma-amino-N-butyrate transaminase assay method; ND means no data
Assay data:4 Tested
In vivo inhibition of succinate formation in the synaptosomal Gamma-amino-N-butyrate transaminase assay at 100 uM
Assay data:8 Tested
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 5 uM after 3 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 5 uM after 6 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 2.5 uM after 3 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 2.5 uM after 6 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 5 uM after 4.5 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 1.25 uM after 3 h
Inhibition of Rattus norvegicus (rat) brain gamma-amino butyrate aminotransferase using gamma-amino butyrate as substrate assessed as decrease in NADPH generation after 30 min by spectrophotometric analysis
Assay data:19 Active, 14 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 0.625 uM after 3 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 0.625 uM after 6 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 2.5 uM after 4.5 h
In vitro percentage inhibition activity against GABA-T enzyme at a concentration of 1.25 uM after 4.5 h
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