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Binding affinity to recombinant human C5a assessed as loss of super secondary structure at > 10 uM incubated for 1 hr at 4 degC by circular dichroism analysis
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed Citation
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
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Binding affinity to recombinant human C5a assessed as conformational change at 1 to 100 uM incubated for 1 hr at 4degC by circular dichroism analysis
Binding affinity to recombinant human C5a assessed as conformational change =< 1 uM at 4 degC incubated for 1 hr by circular dichroism analysis
Inhibition of C5 complement protein in 2% human serum incubated for 15 mins
Assay data:3 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 2 to 4 M by circular dichroism analysis
Assay data:1 Active, 1 Tested
Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 2 to 8 M by circular dichroism analysis
Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M by circular dichroism analysis
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