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Concentration required for inhibitory activity against human sorbitol dehydrogenase (SDH)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
% Ability to inhibit lower sciatic nerve fructose that became elevated in diabetic nerve in streptozotocin diabetic rat model at 1 mg/kg; ND is not determined
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
In vitro inhibitory activity against human SDH
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Concentration required for 50% in vitro inhibition of recombinant human sorbitol dehydrogenase (h-SDH)
Assay data:44 Active, 44 Activity ≤ 1 µM, 44 Tested
In vitro inhibition against human recombinant Sorbitol dehydrogenase
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
In vitro inhibition against human recombinant sorbitol dehydrogenase
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of sorbitol dehydrogenase from sheep liver (40 U/mg of protein)
Assay data:20 Tested
Concentration required for 50% in vitro inhibition in sheep liver sorbitol dehydrogenase (s-SDH)
Assay data:20 Active, 9 Activity ≤ 1 µM, 20 Tested
In vitro inhibitory activity against sorbitol dehydrogenase (SD) from sheep liver
In vitro inhibitory activity against sorbitol dehydrogenase (SD) from sheep liver; Not active
Assay data:6 Tested
Concentration required for 50% for in vitro activity against human SDH (sorbitol dehydrogenase)
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Concentration required for 50% in vitro activity against human SDH (sorbitol dehydrogenase)
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Concentration required for 50% for in vitro activity against human SDH (sorbitol dehydrogenase); ND is not determined
Inhibition sorbitol dehydrogenase by spectrophotometric analysis
Assay data:16 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
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