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Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
SummaryPubMed Citation
Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting
Assay data:7 Active, 1 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human GLT1 expressed in HEK293 cells assessed as reduction of [3H]-glutamate uptake at 100 uM after 10 mins by scintillation counting relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human EAAT2 expressed in HEK293 cells at 75 uM by [3H]D-Asp uptake assay
Inhibition of human EAAT2 expressed in HEK293 cells at 100 uM by [3H]D-Asp uptake assay
Assay data:7 Tested
Inhibition of human EAAT2 expressed in HEK293 cells at 300 uM by [3H]D-Asp uptake assay
Assay data:11 Tested
Inhibition of human EAAT2 expressed in HEK293 cells at 1000 uM by [3H]D-Asp uptake assay
Assay data:2 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of EAAT2-mediated D-aspartate transport at 100 uM
Inhibition of EAAT3-mediated D-aspartate transport at 100 uM
Inhibition of human GLT1 expressed in HEK293 cells assessed as reduction of [3H]-glutamate uptake at 500 uM after 10 mins by scintillation counting
Assay data:5 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Inhibition of human EAAT2 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting method
Inhibition of [3H]-D-aspartate uptake at human EAAT2 expressed in HEK293 cells after 6 mins by scintillation counting
Assay data:6 Tested
Inhibition of human EAAT2 expressed in HEK293 cells by [3H]-D-Asp uptake assay
Assay data:12 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of EAAT2 (unknown origin) expressed in african green monkey COS7 cells using [3H]-glutamic acid as substrate after 10 mins by scintillation counting
Inhibition of human cloned EAAT2 expressed in HEK293 cells up to 300 to 1000 uM by [3H]-D-Asp uptake assay
Assay data:19 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
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