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Compound was evaluated for functional potency and efficacy at rat Nicotinic acetylcholine receptor subtype DA release
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 2.5*10e-9-2.5*10e-5 M was reported
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -10 - 10 E -4 M was reported; response was dose related
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -9 - 10 E -6 M was reported
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a particular dose range 5E-9 - 1.5E-8 was reported
Binding affinity towards nicotinic acetylcholine receptor (nAChR) using [3H]cytisine as radioligand in rat brain
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Binding affinity towards nicotinic acetylcholine receptor (nAChR)
Binding ability to displace the binding of [3H]nicotine from rat cortical membranes; Not determined
Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]-nicotine from rat cortical membranes
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity towards Nicotinic acetylcholine receptor by the displacement of [3H]nicotine from rat cortical membranes; Not determined
Assay data:2 Tested
The compound was tested for inhibitory potency against Nicotinic acetylcholine receptor in Rat muscle.
Evaluated for its binding affinity towards Nicotinic acetylcholine receptor in rat brain homogenate
Assay data:13 Active, 6 Activity ≤ 1 µM, 18 Tested
The compound was tested for the inhibition of binding of [3H]epibatidine to central nicotinic acetylcholine receptor (nAChR) in rat brain.
Assay data:8 Active, 6 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor subtype PC12 (ganglionic)
Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested
Compound was evaluated for functional potency and efficacy at rat Nicotinic acetylcholine receptor in PC12 cells (ganglionic)
Compounds was evaluate for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 2.5*10e-9-7.5*10e-5 M was reported
Compound was evaluated for potency and efficacy at rat Nicotinic acetylcholine receptor subtype DA release;
Binding affinity towards neuronal nicotinic receptor using [3H]cytisine as radioligand in rat forebrain homogenates
Binding affinity towards nicotinic acetylcholine receptor using [125I]alpha-bungarotoxin as radioligand in rat forebrain homogenates
Assay data:11 Active, 6 Activity ≤ 1 µM, 34 Tested
Binding affinity towards nicotinic acetylcholine receptor using [125I]alpha-bungarotoxin as radioligand in rat forebrain homogenates; ND= Not determined
Assay data:10 Tested
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