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Binding affinity to GPR88 in mouse striatal membrane by filtration method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at GPR88 in GPR88 knockout mouse striatal membrane assessed as [35S] GTPgammaS binding at 100 uM incubated for 1 hr by liquid scintillation counting method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at wild type GPR88 expressed in C57BL/6J mouse striatal membrane assessed as [35S] GTPgammaS binding incubated for 1 hr by liquid scintillation counting method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at wild type GPR88 expressed in mouse striatal membrane assessed as [35S] GTPgammaS binding incubated for 1 hr by liquid scintillation counting method
Agonist activity at wild type GPR88 in mouse striatal membrane assessed as maximum efficacy incubated for 1 hr in presence of [35S]GTPgammaS by scintillation counting method relative to control relative to control
Agonist activity at wild type GPR88 in C57BL/6J mouse striatal membrane assessed as maximum efficacy incubated for 1 hr in presence of [35S]GTPgammaS by scintillation counting method relative to control relative to control
Agonist activity at GPR88 in mouse striatal membrane assessed as [35S]-GTPgammaS-binding by liquid scintillation counting relative to control
Assay data:2 Tested
Agonist activity at GPR88 in mouse striatal membrane assessed as [35S]-GTPgammaS-binding by liquid scintillation counting
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Agonist activity at GPR88 in wild type mouse striatal membranes assessed as increase in [35S]-GTPgammaS binding after 1 hr by liquid scintillation counting
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Agonist activity at GPR88 in mouse striatal membranes assessed as increase in [35S]-GTP-gammaS binding
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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