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Percent binding affinity against 5-hydroxytryptamine receptor
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Subcutaneous dose giving half-maximal decrease of 5-HTP formation in the rat brain (limbic)
Assay data:17 Tested
Evaluated for receptor mediated feedback inhibition of 5-HTP formation in striatum tissue of rat brain when administered subcutaneously
Assay data:12 Tested
Evaluated for receptor mediated feedback inhibition of 5-HTP formation in limbic tissue of rat brain when administered subcutaneously
Assay data:13 Tested
Evaluated for receptor mediated feedback inhibition of 5-HTP formation in hemisphere of rat brain when administered subcutaneously
Dose corresponding to half-maximal decrease of 5-HTP formation in the limbic and striatal parts of rat brain
Assay data:23 Tested
Ability to elicit head twitches in rats (a serotonin mimetic response)
Assay data:22 Tested
Binding affinity of compound towards serotonin 5-hydroxytryptamine 6 receptor was determined
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
The compound was tested for binding affinity against 5-hydroxytryptamine 6 receptor
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity against 5-hydroxytryptamine 6 receptor from CHO cell membranes using [3H]5-HT as the radioligand.
Compound was tested for the displacement of [3H]5-HT binding to cloned rat 5-hydroxytryptamine 6 receptor stably expressed in CHO cells
Affinity against 5-hydroxytryptamine receptor was determined in rat stomach fundus strip
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Affinity against 5-hydroxytryptamine receptor was determined
The binding affinity was measured on 5-hydroxytryptamine receptor uptake receptor using [3H]- paroxetine as radioligand.
Assay data:2 Tested
Subcutaneous dose giving half-maximal decrease of 5-HTP formation in the rat brain (striatum)
Displacement of [3H]-citalopram from rat forebrain membrane 5-hydroxytryptamine receptor at 10e-7 M
Compound was tested for its inhibitory activity against 5-hydroxytryptamine receptor
Assay data:6 Active, 6 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity at serotonin 5-HT1-type site receptor in rat cortex by displacing [3H]5-HT
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