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InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Late stage results from the probe development effort to identify activators of signal transducer and activator of transcription 3 (STAT3).
Assay data:8 Active, 4 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
RNAi screen for vorinostat resistance genes - Secondary Deconvolution Screen
Assay data:732 Active, 1804 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of Bcl-3 in human MDA-MB-231 cells assessed as reduction in NF-kappaB signalling at 1 uM incubated for 24 hrs by NF-kappaB promoter dependent luciferase reporter gene assay
Assay data:5 Active, 5 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Inhibition of FLAG-tagged Bcl-3 (unknown origin) expressed in HEK293 cells assessed as reduction in Bcl3 binding to its cognate protein partner NFKB1 (p50) incubated for 24 hrs by indirect sandwich ELISA
Assay data:3 Active, 3 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of Bcl-3 in human MDA-MB-231 cells assessed as reduction in NF-kappaB signalling incubated for 24 hrs by NF-kappaB promoter dependent luciferase reporter gene assay
Assay data:8 Active, 5 Activity ≤ 1 µM, 8 Tested
Inhibition of Bcl-3 (unknown origin) in HEK293 cells assessed as reduction in NF-kappaB signalling incubated for 24 hrs by NF-kappaB promoter dependent luciferase reporter gene assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
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