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Inhibitory constant against Kynurenine 3-hydroxylase
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Compound was evaluated for inhibition of rat liver KYN 3-OHase
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Compound was evaluated for the inhibition of rat brain KYN 3-OHase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of rat brain KYN 3-OHase.
Assay data:14 Active, 6 Activity ≤ 1 µM, 14 Tested
Compound was evaluated for inhibition of rat brain KYN 3-OHase
Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver at 10 uM
Assay data:28 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver
Assay data:26 Active, 6 Activity ≤ 1 µM, 27 Tested
Ability to inhibit kynurenine-3-hydroxylase was determined in a competitive inhibition assay.
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
Differences in inhibition of kynurenine-3-hydroxylase by m-NBA versus compound is determined
Assay data:4 Tested
Inhibition of rat liver KYN 3-OHase.
Assay data:11 Active, 1 Activity ≤ 1 µM, 19 Tested
Tested for inhibitory activity against kynurenine 3-hydroxylase at 100 uM concentration
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of rat kidney Kynurenine 3-hydroxylase.
Assay data:21 Active, 18 Activity ≤ 1 µM, 21 Tested
Tested for inhibitory activity against kynurenine 3-hydroxylase
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Tested for inhibitory activity against Kynurenine 3-hydroxylase
Compound was evaluated for ex vivo inhibition of Kynurenine 3-hydroxylase activity in liver of rat after injecting perorally
Assay data:5 Tested
Compound was evaluated for ex vivo inhibition of Kynurenine 3-hydroxylase activity in kidney of rat after injecting perorally
Compound was evaluated for ex vivo inhibition of Kynurenine 3-hydroxylase activity in kidney and liver of rat after injecting perorally
Inhibition of kynurenine-3-hydroxylase in rat liver homogenates assessed as effect on production of 3-hydroxy kynurenine up to 125 uM incubated for 1 hr by HPLC
Inhibition of rat liver KMO using [3,5-3H]-kynurenine substrate
Inhibition of rat KMO
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