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Inhibition of Trypsin (unknown origin) using H-D-CHA -Ala-Arg-AMC.2AcOH substrate assessed as residual activity at 10 uM incubated for 15 mins prior to substrate addition measured for 2 hrs
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human trypsin using hilyte fuor 488-labeled casein as substrate after 30 mins by green protease fluorometric assay
Assay data:5 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Inhibition of human trypsin using chromogenic substrate S2222 by dixon plot analysis plot
Assay data:2 Tested
Inhibition of human trypsin in presence of Zn2+
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human trypsin in presence of EDTA
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Binding affinity to trypsin assessed as protein labeling at 2 uM after 15 mins by fluorescent scanning method
Assay data:6 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Tight binding inhibition of human trypsin expressed in Drosophila melanogaster S2 cells using Boc-QAR-AMC as substrate incubated for 15 mins prior to substrate addition measured for 30 mins by fluorimetric analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of Trypsin (unknown origin) using H-D-CHA -Ala-Arg-AMC.2AcOH substrate incubated for 15 mins prior to substrate addition measured for 2 hrs
Assay data:1 Active, 1 Tested
Inhibition of human trypsin at 10 uM
Inhibition of trypsin (unknown origin) using S-2222 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 s by amidolytic method
Assay data:8 Active, 6 Activity ≤ 1 µM, 8 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of trypsin (unknown origin) using N-alpha-benzoyl-DL-arginine-p-nitroanilide as substrate
Inhibition of trypsin (unknown origin)
Inhibition of trypsin (unknown origin) at 45.5 uM
Assay data:3 Tested
Assay data:3 Active, 4 Tested
Inhibition of trypsin (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis
Assay data:6 Active, 29 Tested
Assay data:4 Tested
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