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A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
SummaryPubMed Citation
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW1463)
Assay data:9 Active, 794 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Inhibition of PRKX (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Inhibition of PRKX (unknown origin) at 1 uM in presence of 100 uM ATP
Assay data:1 Tested
Inhibition of PRKX (unknown origin) at 100 nM
Inhibition of human full length N-terminal GST-tagged PRKX expressed in insect cells using kemptide as substrate at 100 nM by radiometric assay in presence of [32P]ATP
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
Inhibition of human PrKX assessed as enzyme activity at 1 uM relative to control
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (NCIH716)
Assay data:13 Active, 794 Tested
Human kinome siRNA screen in A549-BTR and MDA-231-1833-BTR cells
Assay data:49 Active, 714 Tested
Inhibition of human PrKX assessed as residual activity at 1 uM relative to control
Competitive binding affinity to PRKX (unknown origin) at 10 uM in presence of ATP relative to control
Assay data:4 Tested
Inhibition of PRKX (unknown origin) at 10 uM relative to control
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Inhibition of PRKX (unknown origin) assessed as remaining activity at 10 uM relative to control
Assay data:2 Tested
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