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Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C at helix 45 of 18S rRNA at 50 uM after 48 hrs by nucleotide resolution sequencing analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Assay data:1 Active, 243 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Stabilization of full length recombinant NAT10 (unknown origin) by DSLS based analysis
Assay data:2 Active, 3 Tested
Binding affinity to recombinant NAT10 acetyltransferase domain (494 to 753 residues) (unknown origin) by isothermal titration calorimetry
Assay data:1 Active, 2 Tested
Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C level at 10 to 50 uM after 48 hrs by LC-MS assay
Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C level at 50 uM after 48 hrs by Northern blot assay
Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C at helix 34 of 18S rRNA at 50 uM after 4 days by UV-HPLC analysis
Inhibition of NAT10-catalyzed RNA cytidine acetylation in human HeLa cells assessed as decrease in ac4C at helix 45 of 18S rRNA at 50 uM after 4 days by UV-HPLC analysis
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