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Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I
Assay data:8 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of geranylgeranylation of P21rap in human PC-3 prostate cancer cells
Assay data:1 Tested
Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assay
Assay data:2 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cells
Inhibition binding constant against Geranylgeranyl transferase type I
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Geranylgeranyl transferase type I (not determined)
Assay data:5 Tested
Inhibition of Geranylgeranyl transferase type I
Assay data:1 Active, 4 Tested
Inhibitory activity against recombinant human Geranylgeranyl transferase type I
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Assay data:9 Active, 1 Activity ≤ 1 µM, 25 Tested
Inhibition binding constant Geranylgeranyl transferase type I
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
In vitro inhibitory activity to reduce the human geranylgeranyl transferase type I (GGPTase-1)-catalyzed incorporation of 3H GGPP (100 nM) into K-Ras-derived peptide
Assay data:20 Active, 13 Activity ≤ 1 µM, 24 Tested
In vitro inhibition of Geranylgeranyl transferase type I
Assay data:10 Tested
In vitro inhibition of geranylgeranyltransferase-1
Assay data:11 Active, 2 Activity ≤ 1 µM, 13 Tested
In vitro inhibitory activity against geranylgeranyltransferase-1 (type I)
Assay data:2 Active, 2 Tested
In vitro inhibition against human Geranylgeranyl transferase type I catalyzed by incorporation of [3H]- GGPP (geranylgeranyl pyrophosphate) into biotinylated peptide corresponding to the c-terminus of human Ki-Ras
Assay data:6 Active, 5 Activity ≤ 1 µM, 15 Tested
Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-transferase type I.
Assay data:32 Active, 13 Activity ≤ 1 µM, 37 Tested
Concentration required to inhibit recombinant human geranylgeranyl transferase type I (GGTase-I) catalyzed incorporation of [3H]GGPP to the C-terminus of human K-Ras.
Assay data:26 Active, 1 Activity ≤ 1 nM, 24 Activity ≤ 1 µM, 26 Tested
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