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Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Late stage results from the probe development efforts to identify inhibitors of Matrix Metalloproteinase-13 (MMP-13).
Assay data:7 Active, 1 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Single concentration validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay
Assay data:85 Active, 1927 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Dose Response validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay
Assay data:92 Active, 7 Activity ≤ 1 µM, 396 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
SAR validation of uHTS RPN11 inhibitor hits using a MMP-2 Fluorescence assay
Assay data:15 Active, 50 Tested
Single concentration validation of Csn-Mediated Deneddylation of Cullin-Ring Ligase Hits Using a MMP-2 Fluorescence Assay
Assay data:179 Active, 541 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Late stage assay provider QFRET-based biochemical high throughput dose response assay to counterscreen inhibitors of ADAM10 and ADAM17 against metalloproteases MMP1, MMP2, MMP8, MMP9, MMP10, MMP13, MMP14, Meprin A, and Meprin B
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Human MMP2 (M10: Matrix metallopeptidase)
Assay data:7 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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