BioAssay by Target (List) for Gene (Select 3683) - PubChem BioAssay - NCBI

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Select item 946111.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (6-100)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94611

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 995862.

Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (120-140)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 99586

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 995853.

Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (110-140)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 99585

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 995844.

Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (100-110)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 99584

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 995835.

Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:9 Active, 7 Activity ≤ 1 µM, 9 Tested

AID:: 99583

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 946166.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(30-300)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94616

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 946157.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(3-10)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94615

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 946148.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(2-8)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94614

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 946139.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(12-60)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94613

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9461210.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range(0.03-0.5)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94612

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9958711.

Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (20-30)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 99587

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9461012.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (6-10)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94610

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460913.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (30-170)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94609

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460814.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (30-150)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94608

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460715.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (3-18)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94607

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460616.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (3-10)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94606

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460517.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-9)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 94605

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460418.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-30)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94604

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460319.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (2-2)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94603

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9460220.

Inhibition of LFA-1 mediated JY-8 cell adhesion to ICAM-1, range (100-600)

Source:: ChEMBL

Protein Targets:: Integrin alpha-L; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 94602

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (110)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (5)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (99)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (119)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (146)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (140)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (18)
BioAssays deposited by other experimentalists

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