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An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
In vitro Hsp60 chaperone activity in mitochondrial malate dehydrogenase (MDH) refolding assay; ND not determined
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
In vitro Hsp60 chaperone activity in mitochondrial malate dehydrogenase (MDH) refolding assay
Assay data:9 Tested
Competitive binding to human heat shock protein Hsp60; 60-90%
Competitive binding to human heat shock protein Hsp60; 20-60%
Competitive binding to human heat shock protein Hsp60
Assay data:6 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 40 to 60 mins by spectrometric analysis
Assay data:8 Active, 1 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human mitochondrial HSP60/10-mediated refolding of the denatured malate dehydrogenase
Assay data:4 Active, 24 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to 60 kDa HSP60 in human HePAD38 cells infected with HBV assessed as protein labelling at 20 uM after 1 hr by photoaffinity labelling in-situ fluorescence gel-based LC-MS/MS analysis
Assay data:1 Active, 1 Tested
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