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TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Procainamide: 2500 uM) in OCTN2-expressing HRPE cells
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Desipramine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Dopamine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Guanidine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, MPP+: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, MPTP: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Methanphetamine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Nicotine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Norepinephrine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, DMA: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Serotonin: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, THA: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, TMA: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Thiamine: 2500 uM) in OCTN2-expressing HRPE cells
TP_TRANSPORTER: uptake in OCTN2-expressing HRPE cells
Assay data:4 Tested
Inhibition of rat kidney brush border membrane OCTN2 transporter assessed as [3H]carnitine uptake after 30 mins relative to control
Inhibition of rat kidney brush border membrane OCTN2 transporter assessed as [3H]carnitine uptake after 10 mins
Assay data:3 Tested
TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.025 uM, Choline: 2000 uM) in OCTN2-expressing HRPE cells
Ratio of drug transport assessed as OCTN2 transporter mediated effective permeability in rat jejunum at 76 uM in absence of L-carnitine to drug transport assessed as OCTN2 transporter mediated effective permeability in rat jejunum at 76 uM in presence of L-carnitine
Assay data:2 Tested
TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.02 uM, Cefadroxil: 2500 uM) in OCTN2-expressing HeLa cells
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