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Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells by whole cell patch clamp method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of rat L type calcium channel dihydropyridine site at 1 uM
Assay data:2 Tested
Displacement of [3H]desmethoxyverapamil from verapamil binding site of L type calcium channel in rat heart
Assay data:2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at L-type calcium channel in rat aorta
Assay data:2 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [3H]diltiazem from benzodiazepine binding site of L-type calcium channel in Wistar rat cerebral cortex membrane
Assay data:9 Active, 1 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes
Assay data:2 Active, 1 Activity ≤ 1 µM, 3 Tested
Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes at 10 uM
Inhibition of voltage-dependent L-type calcium channel in rat thoracic aorta ring assessed as effect on high K+ induced contraction by Magnus method
Assay data:16 Active, 7 Activity ≤ 1 µM, 16 Tested
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells at 15 uM by whole cell patch clamp method at -50 mV voltage
Assay data:1 Active, 1 Tested
Inhibition of rat L type calcium channel benzothiazepine site at 1 uM
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells at 100 uM by whole cell patch clamp method
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells assessed as decrease in amplitude at 15 uM by whole cell patch clamp method
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells assessed as inhibition of peak inward current at 15 uM by whole cell patch clamp method at -20 to 40 mV voltage
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells at 15 uM by whole cell patch clamp method at 2 Hz
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells at 15 uM by whole cell patch clamp method at 4 Hz
Inhibition of L-type calcium channel in Wistar rat tail artery smooth muscle cells assessed as blockade of barium-sensitive inward rectifying current by whole cell patch-clamp assay
Assay data:1 Active, 3 Tested
Inhibition of L-type calcium channel in Wistar rat tail artery smooth muscle cells assessed as blockade of barium-sensitive inward rectifying current at 10 uM by whole cell patch-clamp assay
Displacement of [3H]nitrendipine from calcium channel receptors (CCRs) from rat cortex homogenate
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Percent increase in current at -20 mV on L-type [Ca2+] channels in rat RIN-m5F at 3 insulinoma cells (n = 5)
Percent increase in current at -20 mV on L-type [Ca2+] channels in rat RIN-m5F at 3 insulinoma cells (n = 8)
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