BioAssay by Target (List) for Gene (Select 29340) - PubChem BioAssay - NCBI

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Select item 1651141.

Inhibition of Protein kinase C isolated from rat brain

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:5 Tested

AID:: 165114

Summary Related BioAssays by Target

Select item 1651062.

Inhibition of rat brain protein kinase C(PKC) in 10%DMSO.

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:7 Active, 6 Activity ≤ 1 µM, 7 Tested

AID:: 165106

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1651073.

Inhibition of partially purified rat brain protein kinase C

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 165107

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 1651084.

In vitro inhibition of protein kinase C from rat brain.

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested

AID:: 165108

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 1651095.

Inhibition of Protein kinase C (PKC) activity, Enzyme assay done using gamma-[32P]ATP and synthetic peptide substrates

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:2 Tested

AID:: 165109

Summary PubMed Citation Related BioAssays by Target

Select item 1651106.

Inhibition of Protein kinase C of Rat brain

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 165110

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1651117.

Inhibition of protein kinase C

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:2 Active, 2 Activity ≤ 1 µM, 6 Tested

AID:: 165111

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1651128.

Inhibitory activity against protein kinase C of rat brain

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:3 Active, 24 Tested

AID:: 165112

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 1651139.

Inhibition of purified rat brain protein kinase C (RB-PKC)

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:11 Active, 9 Activity ≤ 1 µM, 11 Tested

AID:: 165113

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16510510.

Inhibition of rat brain protein kinase C(PKC) in 1%DMSO.

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested

AID:: 165105

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16511511.

Inhibition of protein kinase C (PKC) from rat brain homogenate

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:7 Active, 5 Activity ≤ 1 µM, 11 Tested

AID:: 165115

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16511712.

Displacement of [3H]PDBU from protein kinase C

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:8 Tested

AID:: 165117

Summary PubMed Citation Related BioAssays by Target

Select item 16511813.

Inhibitory concentration required against Protein kinase C (isolated from rat brain) in PKC assay performed with 4 ug phosphatidyl serine:diacylglycerol (2:1)

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:13 Active, 23 Tested

AID:: 165118

Summary Compounds, Active Related BioAssays by Target

Select item 16511914.

Inhibition of Protein kinase C of rat brain using phosphatidyl serine: di-acyl glycerol (2:1) (Not active at 100 uM)

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:3 Tested

AID:: 165119

Summary Related BioAssays by Target

Select item 16512015.

Inhibition of Protein kinase C of rat brain using phosphatidyl serine: di-acyl glycerol (2:1)

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:12 Tested

AID:: 165120

Summary Related BioAssays by Target

Select item 16512116.

Tested for inhibition of protein kinase C from rat brain

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:18 Active, 18 Activity ≤ 1 µM, 18 Tested

AID:: 165121

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 16512217.

Inhibition of protein kinase C

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:5 Active, 3 Activity ≤ 1 µM, 14 Tested

AID:: 165122

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16512318.

In vitro for inhibitory activity against protein kinase C from rat brain

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:16 Active, 14 Activity ≤ 1 µM, 17 Tested

AID:: 165123

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 16510319.

Inhibition of protein kinase C from rat brain (PKC)

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 165103

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 16510220.

Inhibition of protein kinase C (PKC) in rat brain

Source:: ChEMBL

Protein Targets:: Protein kinase C alpha type; ...
Total:: 8

Assay data:18 Active, 18 Activity ≤ 1 µM, 18 Tested

AID:: 165102

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioActivity

Active Compounds (40)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (29)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (50)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (65)
BioAssays extracted from the literature

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