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Mean inhibitory concentration against [3H]ifenprodil binding to porcine N-methyl-D-aspartate (NMDA) glutamate receptor; n=1
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MK-801 site of glutamate receptor at 10 uM
Assay data:1 Tested
Inhibition of MK-801 site of glutamate receptor at 100 nM
Inhibition of MK-801 site of glutamate receptor at 1 nM
Inhibition of agonist site of NMDA receptor at 10 uM
Inhibition of agonist site of NMDA receptor at 100 nM
Inhibition of agonist site of NMDA receptor at 1 nM
Percentage binding to NMDA at 10 uM
Percent inhibition against NMDA receptor at a compound concentration of 1 uM
Assay data:2 Tested
Percent inhibition against PCP receptor at 1 uM
Mean inhibitory concentration against [3H]MK-801 binding to porcine N-methyl-D-aspartate (NMDA) glutamate receptor; -=not tested
Specific binding of [3H]ifenprodil to N-methyl-D-aspartate (NMDA) glutamate receptor remaining in presence of 100 uM inhibitor
Assay data:4 Tested
Mean inhibitory concentration against [3H]ifenprodil binding to porcine N-methyl-D-aspartate (NMDA) glutamate receptor; n=3
Assay data:3 Active, 2 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to NMDA receptor
Mean inhibitory concentration against [3H]MK-801 binding to porcine N-methyl-D-aspartate (NMDA) glutamate receptor; n=3
Assay data:3 Active, 1 Activity ≤ 1 µM, 14 Tested
Inhibition of [3H]-Ro-25-6981 binding to NMDA receptor
Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested
Mean inhibitory constant against porcine N-methyl-D-aspartate (NMDA) glutamate receptor; n=3
Assay data:14 Active, 8 Activity ≤ 1 µM, 15 Tested
Mean inhibitory constant against porcine N-methyl-D-aspartate (NMDA) glutamate receptor; n=1
Inhibitory activity against Phencyclidine receptor using [3H]-TCP at 10e5 (M)
Binding affinity towards PCP receptor in guinea pig brain membrane using radiolabeled ligand [3H]TCP (1-[1-(2-thienyl)cyclohexyl]piperidine) was determined
Assay data:4 Active, 9 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
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