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Percent stimulation of [35S]GTP-gamma-S, binding to G alpha i1 at 5E-5 M of basal for 30 minutes; not determined
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Galphai-mediated LPA-stimulated cell invasion in human SKOV3 cells
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels by scintillation spectroscopy
Assay data:5 Active, 27 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels at 100 uM by scintillation spectroscopy
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels at 10 uM by scintillation spectroscopy
Assay data:6 Tested
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels at 50 uM by scintillation spectroscopy
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels at 5 uM by scintillation spectroscopy
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels at 10 uM by scintillation spectroscopy relative to basal
Activation of human Gi protein alpha1 subunit expressed in Escherichia coli assessed as protein bound [35S]GTPgammaS levels at 1 uM by scintillation spectroscopy
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Percent stimulation of [35S]GTP-gamma-S, binding to G alpha i1 at 5E-5 M of basal for 30 minutes
Assay data:34 Tested
Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha i3; not determined
Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha i1; not determined
Concentration required to stimulate binding of [35S]GTP-gamma-S, with G alpha i1
Assay data:6 Active, 29 Tested
Probe Development Summary for Inhibitors of RGS12 GoLoco Motif Activity
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore)
Assay data:1029 Active, 234161 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Green Fluorophore)
Assay data:12 Active, 3 Activity ≤ 1 µM, 1279 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Binding affinity to GDP-bound human Galphai1 expressed in Escherichia coli BL21 in H2O/DMSO-d6 at 500 uM by STD NMR analysis
Assay data:1 Active, 2 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
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