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Inhibition LPS-induced JNK1/2 phosphorylation at Thr183/Tyr15 in mouse RAW264.7 cells at 10 uM administered 30 mins prior to LPS challenge measured after 30 mins by Western blotting analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
TLR-pathway-mouse_LPS ligand_TNF readout
Assay data:130 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
TLR-pathway-mouse_P3C ligand_TNF readout
Assay data:115 Active, 756 Tested
TLR-pathway-mouse_LPS ligand_NFkB readout
Assay data:137 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_NFkB readout
Assay data:147 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_TNF readout
TLR-pathway-mouse_P3C ligand_NFkB readout
Assay data:128 Active, 756 Tested
Inhibition LPS-induced JNK1/2 phosphorylation at Thr183/Tyr15 in mouse RAW264.7 cells at 40 uM administered 30 mins prior to LPS challenge measured after 30 mins by Western blotting analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition LPS-induced JNK1/2 phosphorylation at Thr183/Tyr15 in mouse RAW264.7 cells at 20 uM administered 30 mins prior to LPS challenge measured after 30 mins by Western blotting analysis
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Inhibition of LPS-induced JNK phosphorylation in mouse RAW264.7 cells at 20 uM by Western blotting analysis
Inhibition of IFNgamma-induced JNK phosphorylation in mouse RAW264.7 cells at 20 uM by Western blotting analysis relative to untreated control
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of LPS-induced JNK1/2 phosphorylation in mouse RAW264.7 cells after 45 mins by Western blot analysis
Activation of JNK1 in mouse RAW264.7 cells assessed as phosphorylation at Thr183/Tyr185 at 50 uM after 30 mins to 4 hrs by Western blotting analysis
Activation of JNK1 in mouse RAW264.7 cells assessed as phosphorylation at Thr183/Tyr185 at 50 uM after 30 mins by Western blotting analysis
Inhibition of JNK1-dependent LPS-stimulated TNFalpha release in mouse RAW264.7 cells at 12.5 uM after 1 hr by sandwich immunoassay relative to control
Inhibition of TNF-alpha-induced c-JUN phosphorylation in mouse B16-F10 cells by TR-FRET assay
Assay data:2 Active, 3 Tested
Inhibition of JNK1 in mouse RAW264.7 cells assessed as inhibition of c-Jun phosphorylation incubated for 30 mins by cellular assay
Assay data:12 Active, 7 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of JNK phosphorylation in R848-stimulated mouse BMDC cells at 1 to 4 uM treated for 2 hrs followed by R848 stimulation for 12 hrs by western blot analysis
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