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Inverse agonist activity at ERRgamma in mouse C2C12 cells assessed as inhibition of [3H]-palmitate-BSA oxidation at 100 nM after 48 hrs by scintillation counting method relative to vehicle-treated control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inverse agonist activity at ERRgamma in mouse C2C12 cells assessed as downregulation of SHP transcript levels at 100 nM after 48 hrs by real-time PCR method relative to control
Inverse agonist activity at GAL4-DNA binding domain-fused mouse ERRgamma ligand binding domain expressed in African green monkey CV1 cells assessed as decrease in receptor transcriptional activity after 45 hrs by luciferase reporter gene assay
Assay data:12 Active, 6 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in MCAD mRNA levels at 1 uM by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in ATP5b mRNA levels at 1 uM by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in ERRalpha mRNA levels at 1 uM by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in SHP mRNA levels at 1 uM by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in ATP5b protein levels at 0.5 to 5 uM by Western blotting method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in MCAD protein levels at 0.5 to 5 uM by Western blotting method
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in MCAD mRNA levels by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in ATP5b mRNA levels by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in ERRalpha mRNA levels by quantitative real time PCR assay
Increase in ERRgamma mediated transcriptional activity in primary mouse embryonic fibroblasts assessed as increase in SHP mRNA levels by quantitative real time PCR assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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