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Inhibition of fetal rat (alpha1)2beta1gammadelta expressed in Xenopus laevis oocytes assessed as dissociation rate constant for inhibition of acetylcholine-induced channel current response at 100 nM at -70 mV holding potential by two-electrode voltage-clamp assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as dissociation rate constant for inhibition of acetylcholine-induced channel current response at -70 mV holding potential by two-electrode voltage-clamp assay
Assay data:4 Tested
Negative allosteric modulation of rat alpha1betagammadelta nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at 30 uM at -40 mV holding potential by two-electrode voltage clamp method relative to acetylcholine alone
Assay data:2 Tested
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