Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Antagonist activity at rat CaSR expressed in HEK293 cells assessed as inhibition of Ca2+-induced inositol monophosphate accumulation after 1 hr by FRET assay
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Compound was evaluated for accumulation of [3H]- IP in CHO (CaSR) cells expressing rat cloned calcium sensing receptor
Assay data:19 Tested
Maximal stimulation of [3H]-inositol phosphates production in CHO cells expressing rat Calcium sensing receptor (CaSR) at 10 mM [Ca2+]
Assay data:17 Tested
Ability to stimulate [3H]inositol phosphates accumulation in CHO cells expressing rat Calcium sensing receptor (CaSR) at 2 mM [Ca2+]
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptor
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation at 10 uM
Assay data:31 Tested
Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation at 1 uM
Assay data:23 Tested
Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation
Assay data:8 Active, 4 Activity ≤ 1 µM, 8 Tested
Negative allosteric modulator activity at rat calcium sensing receptor expressed in HEK cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at rat CaSR expressed in CHO cells assessed as increase of calcium-induced inositol phosphate accumulation at 10 uM after 24 hrs by HTRF assay relative to calcium
Assay data:10 Tested
Agonist activity at CaSR in rat parathyroid cells assessed as inhibition of PTH (1 to 84 residues) production in presence of Cacl2 by ELISA
Assay data:13 Active, 2 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 15 Tested
Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 10 uM in presence of 3 mM extracellular Ca2+ by IP-one assay
Assay data:7 Tested
Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 3 uM in presence of 3 mM extracellular Ca2+ by IP-one assay
Assay data:18 Tested
Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 10 uM in presence of 2 mM extracellular Ca2+ by IP-one assay
Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 3 uM in presence of 2 mM extracellular Ca2+ by IP-one assay
Assay data:6 Tested
Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production at 0.1 uM in presence of 3 mM extracellular Ca2+ by IP-one assay
Assay data:1 Tested
Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one assay
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Rat CaS receptor (Calcium-sensing receptor)
Assay data:5 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at rat CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on