BioAssay by Target (List) for Gene (Select 2217) - PubChem BioAssay - NCBI

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Select item 4767741.

Ratio of RF-Pen-TGHFG-Sar-NMeLeu-YPC IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:12 Tested

AID:: 476774

Summary PubMed Citation Related BioAssays by Target

Select item 19042.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 4045553.

Inhibition of human IgG binding to soluble human FcRn by ELISA

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:56 Active, 9 Activity ≤ 1 µM, 178 Tested

AID:: 404555

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4045564.

Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:105 Active, 52 Activity ≤ 1 µM, 175 Tested

AID:: 404556

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4045575.

Binding affinity to human FcRn at pH 7.4 by surface plasmon resonance assay

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:17 Active, 9 Activity ≤ 1 µM, 24 Tested

AID:: 404557

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4767666.

Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISA

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:27 Active, 22 Activity ≤ 1 µM, 30 Tested

AID:: 476766

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4767677.

Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:8 Active, 5 Activity ≤ 1 µM, 8 Tested

AID:: 476767

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4767688.

Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assay

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:5 Active, 5 Activity ≤ 1 µM, 8 Tested

AID:: 476768

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4767699.

Ratio of QRF-Asp-TGHFGGLYP-Lys-NGP IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:5 Tested

AID:: 476769

Summary PubMed Citation Related BioAssays by Target

Select item 47677010.

Ratio of RFCTGHFGGLYPC IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:1 Tested

AID:: 476770

Summary PubMed Citation Related BioAssays by Target

Select item 47677111.

Ratio of RF-Pen-TGHF-valerolactam-NMeLeu-YPC IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:1 Tested

AID:: 476771

Summary PubMed Citation Related BioAssays by Target

Select item 47677212.

Ratio of RF-Pen-NMeAla-GHF-X-NMeLeu-YPC IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:1 Tested

AID:: 476772

Summary PubMed Citation Related BioAssays by Target

Select item 47677313.

Ratio of RF-Asp-TGHFG-Sar-NMeLeu-YP-Lys IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:1 Tested

AID:: 476773

Summary PubMed Citation Related BioAssays by Target

Select item 150858814.

RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:790 Active, 18119 Tested

AID:: 1508588

Select item 47677515.

Ratio of RF-Pen-TG-4GuPhe-G-Sar-NMeLeu-YPC IC50 to compound IC50 for soluble human FcRn

Source:: ChEMBL

Protein Target:: IgG receptor FcRn large subunit p51

Assay data:1 Tested

AID:: 476775

Summary PubMed Citation Related BioAssays by Target

Select item 62409916.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 65181017.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 65181118.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 74345419.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 111728120.

A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:555 Active, 64752 Tested

AID:: 1117281

Summary PubMed Citation

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Target

RNAi Target, Active (5)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (6)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (6)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (6)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (8)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (13)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (12)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (13)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (11)
BioAssays deposited by other experimentalists

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