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Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptake
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysis
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 0.72 uM, Deoxycholate: a 100-fold excess) in isolated mouse ileocytes
Assay data:1 Tested
TP_TRANSPORTER: inhibition of Taurocholate accumulation in ASBT-expressing HEK293 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 0.72 uM, CA: a 100-fold excess) in isolated mouse ileocytes
TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 0.72 uM, CDCA: a 100-fold excess) in isolated mouse ileocytes
TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 0.72 uM, GC: a 100-fold excess) in isolated mouse ileocytes
TP_TRANSPORTER: inhibition of Taurocholate uptake (Taurocholate: 0.72 uM, Lithocholate: a 100-fold excess) in isolated mouse ileocytes
TP_TRANSPORTER: uptake in ASBT-expressing HEK293 cells
TP_TRANSPORTER: uptake in isolated mouse ileocytes
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