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Inhibition of Notch1 in mouse MEB5 cells assessed as reduction in NICD expression at 1 uM after 24 hrs in presence of proteasome inhibitor MG132 by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Notch1 in mouse MEB5 cells assessed as reduction in Hes5 expression at 1 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Notch1 in mouse MEB5 cells assessed as reduction in Hes1 expression at 1 uM after 24 hrs by Western blot analysis
Inhibition of Notch1 in mouse MEB5 cells assessed as reduction in NICD expression at 1 uM after 24 hrs by Western blot analysis
Inhibition of recombinant mouse Notch1-RAMIC expressed in MEB5 cells harboring TP1 assessed as luciferase activity at 10 uM after 12 hrs by Dual-Glo luciferase assay (Rvb = 0.258 No_unit)
Inhibition of recombinant mouse Notch1-RAMIC expressed in MEB5 cells assessed as reduction in doxycycline-induced NICD expression at 10 uM after 12 hrs by Western blot analysis
Inhibition of doxycycline-induced recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) activation expressed in human LS174T cells assessed as reduction in NCID expression at 0.5 uM after 12 hrs in presence of proteasome inhibitor MG132 by Western blot analysis
Inhibition of doxycycline-induced recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) activation expressed in human LS174T cells assessed as reduction in NCID expression after 12 hrs by Western blot analysis
Inhibition of doxycycline-induced recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) activation expressed in human LS174T cells assessed as reduction in Hes5 level at 0.05 to 0.3 uM after 12 hrs by Western blot analysis
Inhibition of doxycycline-induced recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) activation expressed in human LS174T cells assessed as reduction in Hes1 level at 0.05 to 0.3 uM after 12 hrs by Western blot analysis
Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycycline-induced NICD expression after 12 hrs by Bright-Glo luciferase reporter gene assay
Assay data:5 Active, 1 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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