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A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of LPS-induced IkappaB-alpha degradation in mouse RAW264.7 cells at 1 to 50 uM pre-incubated for 5 mins before LPS stimulation for 30 hrs by Western blotting method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of LPS-induced IkappaB-alpha phosphorylation in mouse RAW264.7 cells at 1 to 50 uM pre-incubated for 5 mins before LPS stimulation for 30 hrs by Western blotting method
Downregulation of RANKL-induced IkappaB alpha phosphorylation in mouse bone marrow macrophages at 5 to 20 uM after 30 mins by Western blot analysis in presence of M-CSF
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
TLR-pathway-mouse_LPS ligand_TNF readout
Assay data:130 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
TLR-pathway-mouse_P3C ligand_TNF readout
Assay data:115 Active, 756 Tested
TLR-pathway-mouse_LPS ligand_NFkB readout
Assay data:137 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_NFkB readout
Assay data:147 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_TNF readout
TLR-pathway-mouse_P3C ligand_NFkB readout
Assay data:128 Active, 756 Tested
Effect on LPS-induced IkappaBalpha phosphorylation in mouse RAW264.7 cells at 3.1 to 25 uM preincubated for 15 mins followed by LPS challenge measured after 10 mins by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of LPS-induced IkappaBalpha phosphorylation in mouse RAW264.7 cells at 25 uM preincubated for 15 mins followed by LPS challenge measured after 15 to 60 mins by Western blot analysis
Inhibition of LPS stimulated IkappaBaplha phosphorylation in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 6 hrs by Western blot analysis
Assay data:2 Tested
SummaryRelated BioAssays by Target
Inhibition of IkappaB phosphorylation in mouse LPS-induced RAW264.7 cells at 0.1 to 0.4 uM incubated for 2 hrs prior to LPS-challenge measured after 30 mins by Western blot analysis
Inhibition of IkappaB phosphorylation in mouse RAW264.7 cells assessed as decrease in LPS-induced phospho-IkappaBalpha level at 75 uM incubated for 2 hrs prior to LPS-challenge measured after 30 mins by Western blot analysis
Inhibition of IkappaBalpha degradation in mouse LPS-induced RAW264.7 cells assessed as increase in cytosolic IkappaB level at 0.1 to 0.4 uM incubated for 2 hrs prior to LPS-challenge measured after 30 mins by Western blot analysis
Inhibition of IkappaBalpha degradation in mouse LPS-induced RAW264.7 cells assessed as increase in cytosolic IkappaB level at 75 uM incubated for 2 hrs prior to LPS-challenge measured after 30 mins by Western blot analysis
Inhibition of IkappaBalpha in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated NF-kappaB p65 subunit translocation to nucleus at 0.1 to 0.4 uM incubated for 2 hrs prior to LPS-challenge measured after 30 mins by Western blot analysis
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