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Binding affinity to MERTK in cuprizone-challenged C57BL/6 mouse brain CC/HC region assessed as maximum binding at 18.1 nM by autoradiography
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to MERTK in cuprizone-challenged C57BL/6 mouse whole brain assessed as maximum binding at 18.1 nM by autoradiography
Binding affinity to MERTK in cuprizone-challenged C57BL/6 mouse brain CC/HC region assessed as dissociation constant at 18.1 nM by autoradiography
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to MERTK in cuprizone-challenged C57BL/6 mouse whole brain assessed as dissociation constant at 18.1 nM by autoradiography
Invivo inhibition of MERTK in NSG mouse xenografted with human 697 cells assessed as reduction in MERTK phosphorylation at 120 mg/kg, po preincubated for 10 mins followed by vanadate addition and measured after 10 mins by immunoblot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Mer in mouse BaF3 cells
Assay data:32 Active, 30 Activity ≤ 1 µM, 32 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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