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Inhibition of GLS1 in mouse kidney extract at 10 mM
Assay data:1 Active, 14 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of mouse recombinant GLS1 relative to control
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mouse recombinant GLS1 glutaminase activity at 1 mM
Assay data:1 Active, 1 Tested
Inhibition of GLS1 in mouse kidney extract at 10 mM relative to control
Assay data:6 Tested
Inhibition of GLS1 in mouse kidney extract at 1 mM relative to control
Assay data:1 Tested
Inhibition of GLS1 in mouse brain assessed as inhibition of glutamate production using glutamine as substrate incubated for 1 hr by coupled assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of GLS1 in mouse kidney assessed as inhibition of glutamate production using glutamine as substrate incubated for 1 hr by coupled assay
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as reduction in alpha-ketoglutarate level at 200 mg/kg, po
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as reduction in fumarate level at 200 mg/kg, po
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as reduction in aspartate level at 200 mg/kg, po
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as reduction in malate level at 200 mg/kg, po
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as reduction in glutathione level at 200 mg/kg, po
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as reduction in glutamate level at 200 mg/kg, po
Invivo inhibition of GLS1 in BALB/c mouse xenografted with human HCT-116 cells assessed as increase in glutamine level at 200 mg/kg, po
Inhibition of mouse kidney glutaminase assessed as ammonia formation at 0.1 uM using glutamine as substrate by Nessler's reagent based assay relative to control
Assay data:5 Active, 5 Activity ≤ 1 µM, 6 Tested
Inhibition of mouse kidney glutaminase assessed as ammonia formation using glutamine as substrate by Nessler's reagent based assay
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