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Inhibition of binding to GABA-A central benzodiazepine receptor (Inactive)
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
In vivo total binding of [3H]flunitrazepam (200uCi/kg, 20 min) to GABA-A benzodiazepine receptor of mouse cortex
Assay data:1 Tested
In vivo total binding of [3H]flunitrazepam (200uCi/kg, 20 min) to GABA-A benzodiazepine receptor of mouse cerebellum
In vivo displacement of [3H]flunitrazepam to GABA-A benzodiazepine receptor of mouse hippocampus at 10 mg/kg, 10 min
In vivo displacement of [3H]flunitrazepam to GABA-A benzodiazepine receptor of mouse cortex at 10 mg/kg, 10 min
In vivo displacement of [3H]flunitrazepam to GABA-A benzodiazepine receptor of mouse cerebellum at 10 mg/kg, 10 min
In vivo inhibition of [3H]flunitrazepam binding to mouse brain 10 minute after 15 uM/kg iv dose (ND = no data)
Assay data:4 Tested
Binding affinity for umolar GABA-A central benzodiazepine receptor
In vivo inhibition of specific [3H]flunitrazepam binding in mouse brain 10 minute after iv administration of 15 uM/Kg
Assay data:12 Tested
Inhibition of binding to GABA-A benzodiazepine receptor (not tested)
Inhibition of binding to GABA-A central benzodiazepine receptor (not tested)
Assay data:2 Tested
Inhibition of binding to GABA-A central benzodiazepine receptor (no data)
Inhibition of binding to GABA-A central benzodiazepine receptor (Inactive at 80 uM)
In vivo total binding of [3H]flunitrazepam (200uCi/kg, 20 min) to GABA-A benzodiazepine receptor of mouse hippocampus
Inhibition of binding to GABA-A central benzodiazepine receptor
Inhibition of binding to GABA-A central benzodiazepine receptor at 0.2 mg/kg
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Ex vivo displacement of [3H]flunitrazepam from mouse GABA-A benzodiazepine receptor at 3 uM/kg iv dose
Ex vivo displacement of [3H]flunitrazepam from mouse GABA-A benzodiazepine receptor at 30 uM/kg iv dose (Range 5-10%)
Ex vivo displacement of [3H]flunitrazepam from mouse GABA-A benzodiazepine receptor at 1 uM/kg iv dose
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