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Binding affinity to immobilized mouse C-terminal Rhinovirus 3C cleavage site-fused 6xHis-tagged Frizzled-8 CRD (Q33 to G173 resideus) transfected with pDisplay_BirA-ER plasmid in HEK293T cells for biotinylation assessed as protein-compound complex formation at 5 to 50 uM by surface plasmon resonance assay
Assay data:1 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of full length mouse Frizzled-8 transfected in Frizzled-1/2/7 knockout HEK293T cells using lentiviral expression system cotransfected with Renilla luciferase assessed as reduction in Wnt3a signaling by measuring luciferase activity at 64 uM measured after 24 hrs by Dual-Glo luciferase reporter assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of full length mouse Frizzled-8 transfected in Frizzled-1/2/7 knockout HEK293T cells using lentiviral expression system cotransfected with Renilla luciferase assessed as reduction in Wnt3a signaling by measuring luciferase activity at 8 to 64 uM measured after 24 hrs by Dual-Glo luciferase reporter assay
Assay data:1 Active, 1 Tested
Binding affinity to immobilized mouse C-terminal Rhinovirus 3C cleavage site-fused 6xHis-tagged Frizzled-8 CRD (Q33 to G173 resideus) transfected with pDisplay_BirA-ER plasmid in HEK293T cells for biotinylation by surface plasmon resonance assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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